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PHARMA TRIALS

Case Study 1
Industry:
Pharmaceutical.

Product:
InsulCap® InsulPlatinum®.

Scenario:
Large shipment of pharmaceutical goods being sent to Manila by sea freight.

Goods are required to be in a controlled temperature environment during shipment.

Data loggers are installed to monitor the internal and external temperatures.

Shipping company goes into liquidation while ship is at sea.

Ship is allowed to dock in Singapore where goods are unloaded and from there will be sent via air freight to Manila.

Prior to despatch to Manila, freight forwarder applies InsulCap® thermal blankets to control temperature and reduce the risk of excursion.

InsulCap® thermal blankets were in place for 72 hours.

Risk
Exposure to extreme high and/or low temperatures may cause product excursions.

Data Collection
Data loggers reveal temperature on the tarmac in Singapore exceeded 40°C and upon arrival in Manila the goods were again exposed to external temperatures approaching 40°C while on the tarmac.

Outcomes
The Insulcap® thermal blanket delivered temperature profiles that were well within the required temperature range with the product temperature inside the protected pallet not exceeding 30°C.

Goods were delivered without costly excursion loss.

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Case Study 2
Industry:
Pharmaceutical.

Product:
InsulBox® InsulPlatinum®.

Scenario:
Temperature sensitive pharmaceutical products.

Temperature control comparison between InsulBox® and polystyrene box.

Both passive insulation containers included a 1kg frozen gel pack.

Goods left inside warehouse for 30 hours then shipped via road transport for 90 hours.

Total trial time 120 hours.

Temperature of goods required to remain under 8°C.

Risk
Exposure conditions were seasonal spring weather Melbourne to Cairns.

Thermal Protection Provided
InsulBox® profile L300 x W210 x H230mm (A4 size) with InsulPlatinum® double foil, ultra-high performance thermal barrier material.

Data Collection
External and internal temperature data was collected by data loggers on outside surface of the box and inside the InsulBox® and the polystyrene box.

Data Temperature Range – Warehouse
Ambient temperature: maximum 24°C, minimum 22°C.

No temperature spikes.

Data Temperature Range – Inside the Van
Ambient temperature: maximum 37°C, minimum 23°C.
Temperature spikes
+14°C (23°C to 37°C) during hours 3 to 13.
+10°C (27°C to 37°C) during hours 73 to 91.

Outcomes – Warehouse
Both InsulBox® and the Esky maintained internal temperature under 8°C for 28 hours.

During hours 0 to 25 the internal temperature within the InsulBox® was approximately 1.5°C lower than in the polystyrene box.

The internal temperature of both passive insulation systems progressively increased during the trial until after 28 hours it was above 8°C.

Overall, while the two systems performed similarly, the InsulBox® demonstrated a better thermal performance.

Outcomes – Inside the Van
Both InsulBox® and the polystyrene box maintained internal temperature under 8°C for 88 hours.

Between hours 13 to 73 both products maintained virtually identical internal temperature.

After 88 hours the temperature within the polystyrene box rose above 80C.

During hours 3 to 13 and 73 to 91 the internal temperature of the polystyrene box was +1°C higher when ambient temperature spikes occurred.

Overall, while the two systems performed similarly, the InsulBox® demonstrated a better thermal performance at the beginning and end of the journey when the ambient temperature increased.

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